What is VRTX's five-year median EV/EBITDA?

The median, or middle weekly reading, is 21.4× over the last five years. Available history contains 818 weekly observations from Feb 21, 2011 to Oct 19, 2026.

Does a low historical rank mean a stock is a buy?

No. The rank describes a stock’s own history. Changes in growth, financial risk and the business can change the multiple investors pay. P/E uses earnings and P/S uses revenue from the previous twelve months.

Vertex Pharmaceuticals (VRTX) valuation history

Above its usual range

As of Oct 22, 2026

VRTX's EV/EBITDA of 25.2x is higher than 84% of its available weekly readings from the last five years.

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EV/EBITDA at year-end

Last weekly reading of each completed year. Rank runs from lowest (0%) to highest (100%) within the five years available on that date.

VRTX year-end valuation history
Reading date	EV/EBITDA	5-year rank
Dec 29, 2025	26.3×	95%
Dec 30, 2024	Unavailable	Short history
Dec 25, 2023	23.3×	63%
Dec 26, 2022	15.2×	5%
Dec 27, 2021	18.1×	15%
Dec 28, 2020	20.3×	4%
Dec 30, 2019	60.4×	27%
Dec 31, 2018	59.5×	7%
Dec 25, 2017	365.9×	83%
Dec 26, 2016	Unavailable	Short history

Peers on the same measure

Stock	EV/EBITDA	5-year rank
ABBVAbbVie	22.6×	88%
AMGNAmgen	19.9×	91%
GILDGilead Sciences	Unavailable	Unranked
INCYIncyte	11.7×	14%

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Health Care Stocks with Low P/E Ratios and Steady Revenue Growth Stocks Below Their 5-Year Median P/E Stocks Near Their Lowest P/E Ratios in 5 Years

Research on VRTX

No published research on VRTX yet. Read how valuation percentiles work.

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About this history

What is VRTX's current EV/EBITDA?: VRTX's EV/EBITDA of 25.2x is higher than 84% of its available weekly readings from the last five years.
What is VRTX's five-year median EV/EBITDA?: The median, or middle weekly reading, is 21.4× over the last five years. Available history contains 818 weekly observations from Feb 21, 2011 to Oct 19, 2026.
Does a low historical rank mean a stock is a buy?: No. The rank describes a stock’s own history. Changes in growth, financial risk and the business can change the multiple investors pay. P/E uses earnings and P/S uses revenue from the previous twelve months.