What is ILMN's five-year median P/E?

27.8x. Half of ILMN's weekly readings since July 2025 were higher and half were lower. This page has 121 weekly readings, from Jul 1, 2024 to Oct 19, 2026.

Does a low historical rank mean a stock is a buy?

No. The rank compares ILMN only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.

Illumina Inc (ILMN) P/E ratio history

Health Care

$269.42

Latest weekly close · Market cap $41.2B

Historically high

As of Oct 24, 2026

ILMN's P/E of 50.3x is higher than 95% of its weekly readings since July 2025.

Weekly P/E since July 2025

P/E each weekMiddle half of its readingsMedian 27.8×

Median: 27.8×
Low to high: 11.6×–51.9×
Versus median: +81%
History starts: July 2025

P/E

95thpercentile

of its weekly readings since July 2025

Historically high

Growth, last 12 months vs the year before

Revenue: +5%accelerating
EPS: -32%

Price vs revenue and EPS, indexed to 100

Each line starts at 100 at its first positive reading over the last five years. Revenue and EPS change at fiscal quarter ends.

PriceRevenue, last 12 monthsEPS, last 12 months100 = first reading

P/E at each year-end

The last weekly reading of each year, and its percentile against the five years before it.

ILMN P/E at each year-end
Year-end	P/E	5-year percentile
Dec 29, 2025	30.1×	Too little history
Dec 30, 2024	n/a	Too little history

Health Care peers on P/E

Each percentile compares a stock with its own last five years.

Compare ILMN with peers

Health Care peers of ILMN on P/E
Stock	P/E	Versus its own history	5-year percentile
AAgilent Technologies	34.3×	Above its usual range	82
AVTRAvantor Inc	n/a	Not ranked	n/a, not ranked
BIOBio-Rad Laboratories Inc	46.3×	Historically high	91
BRKRBruker Corp	n/a	Not ranked	n/a, not ranked
CRLCharles River Laboratories	n/a	Not ranked	n/a, not ranked

Appears in

Sector: Health Care
Screens: Stocks with Low P/E Ratios and Steady Revenue Growth
Stocks Below Their 5-Year Median P/E
Stocks Near Their Lowest P/E Ratios in 5 Years

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Research on ILMN

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About this history

What is ILMN's current P/E?: ILMN's P/E of 50.3x is higher than 95% of its weekly readings since July 2025.
What is ILMN's five-year median P/E?: 27.8x. Half of ILMN's weekly readings since July 2025 were higher and half were lower. This page has 121 weekly readings, from Jul 1, 2024 to Oct 19, 2026.
Does a low historical rank mean a stock is a buy?: No. The rank compares ILMN only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.