What is PFE's five-year median P/E?

15.0x. Half of PFE's weekly readings over the last five years were higher and half were lower. This page has 310 weekly readings, from Nov 23, 2020 to Oct 26, 2026.

Does a low historical rank mean a stock is a buy?

No. The rank compares PFE only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.

Pfizer (PFE) valuation

Health Care

$29.95

Latest weekly close · Market cap $170.7B

Historically high

Pfizer's P/E of 39.4x is higher than 95% of its weekly readings over the last five years (as of Oct 30, 2026).

Forward P/E 10.4× (analyst estimates, not ranked).

Weekly P/E with its 5-year range

P/E each weekMiddle half of the last 5 years5-year median 15.0×

5-year median: 15.0×
10-year median: 16.0×
5-year low to high: 6.9× to 75.5×
Versus 5-year median: +163%

P/E

95thpercentile

of its weekly readings over the last five years

Growth, last 12 months vs the year before

Revenue: 0%accelerating
EPS: -60%

Price vs revenue and EPS, indexed to 100

Each line starts at 100 at its first positive reading over the last five years. Revenue and EPS change at fiscal quarter ends.

PriceRevenue, last 12 monthsEPS, last 12 months100 = first reading

P/E at each year-end

The last weekly reading of each year, and its percentile against the five years before it.

PFE P/E at each year-end
Year-end	P/E	5-year percentile	P/S	EV/Sales	EV/EBITDA
Dec 29, 2025	14.6×	47	2.3×	3.1×	10.5×
Dec 30, 2024	35.5×	93	2.6×	3.6×	15.3×
Dec 25, 2023	15.7×	63	2.4×	2.9×	n/m
Dec 26, 2022	9.9×	16	2.9×	3.1×	n/m
Dec 27, 2021	16.9×	11	4.9×	5.0×	n/m
Dec 28, 2020	23.6×	Too little history	4.3×	5.1×	n/m

Health Care peers on P/E

Each percentile compares a stock with its own last five years.

Compare PFE with peers

Health Care peers of PFE on P/E
Stock	P/E	Versus its own history	5-year percentile
AXSMAxsome Therapeutics Inc	n/m	Not ranked	n/m, not ranked
BMYBristol Myers Squibb	13.6×	Below its usual range	15
CORTCorcept Therapeutics Inc	204.6×	Historically high	92
ELANElanco Animal Health Inc	n/m	Not ranked	n/m, not ranked
JAZZJazz Pharmaceuticals PLC	14.2×	Historically low	7

Appears in

Sector: Health Care
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Research on PFE

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About this history

What is PFE's current P/E?: Pfizer's P/E of 39.4x is higher than 95% of its weekly readings over the last five years (as of Oct 30, 2026).
What is PFE's five-year median P/E?: 15.0x. Half of PFE's weekly readings over the last five years were higher and half were lower. This page has 310 weekly readings, from Nov 23, 2020 to Oct 26, 2026.
Does a low historical rank mean a stock is a buy?: No. The rank compares PFE only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.