What is IONS's five-year median P/S?

8.2x. Half of IONS's weekly readings over the last five years were higher and half were lower. This page has 808 weekly readings, from May 2, 2011 to Oct 19, 2026.

Does a low historical rank mean a stock is a buy?

No. The rank compares IONS only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.

Ionis Pharmaceuticals Inc (IONS) P/S ratio history

Health Care

$42.93

Latest weekly close · Market cap $7.1B

Within its usual range

As of Oct 24, 2026

IONS's P/S of 8.1x is lower than 52% of its weekly readings over the last five years.

Weekly P/S with its 5-year range

P/S each weekMiddle half of the last 5 years5-year median 8.2×

5-year median: 8.2×
10-year median: 9.4×
5-year low to high: 5.6×–14.3×
Versus 5-year median: -1%

P/S

48thpercentile

of its weekly readings over the last five years

Within its usual range

Growth, last 12 months vs the year before

Revenue: -7%slowing
EPS: n/a

Price vs revenue and EPS, indexed to 100

Each line starts at 100 at its first positive reading over the last five years. Revenue and EPS change at fiscal quarter ends. EPS was not positive in this window, so it is left out.

PriceRevenue, last 12 months100 = first reading

P/S at each year-end

The last weekly reading of each year, and its percentile against the five years before it.

IONS P/S at each year-end
Year-end	P/S	5-year percentile
Dec 29, 2025	13.2×	97
Dec 30, 2024	6.4×	10
Dec 25, 2023	11.8×	86
Dec 26, 2022	6.1×	3
Dec 27, 2021	6.5×	2
Dec 28, 2020	8.5×	16
Dec 30, 2019	10.6×	11
Dec 31, 2018	13.4×	39
Dec 25, 2017	12.6×	3
Dec 26, 2016	24.8×	74

Health Care peers on P/S

Each percentile compares a stock with its own last five years.

Compare IONS with peers

Health Care peers of IONS on P/S
Stock	P/S	Versus its own history	5-year percentile
ABBVAbbVie	7.8×	Historically high	100
AMGNAmgen	6.4×	Historically high	99
ARWRArrowhead Pharmaceuticals Inc	12.4×	Within its usual range	33
BBIOBridgebio Pharma Inc	18.8×	Below its usual range	17
BIIBBiogen	3.7×	Above its usual range	80

Appears in

Sector: Health Care
Screens: Stocks with Low P/E Ratios and Steady Revenue Growth
Stocks Below Their 5-Year Median P/E
Stocks Near Their Lowest P/E Ratios in 5 Years

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Research on IONS

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About this history

What is IONS's current P/S?: IONS's P/S of 8.1x is lower than 52% of its weekly readings over the last five years.
What is IONS's five-year median P/S?: 8.2x. Half of IONS's weekly readings over the last five years were higher and half were lower. This page has 808 weekly readings, from May 2, 2011 to Oct 19, 2026.
Does a low historical rank mean a stock is a buy?: No. The rank compares IONS only with its own past. Slower growth or more risk can justify a lower multiple than before. P/E uses earnings and P/S uses revenue from the last twelve months.